Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of the involvement of p53 in gamma-radiation-induced DNA repair in human lymphoblasts.

International journal of radiation biology - 1 Aug 1998

Mallya S M, Sikpi M O

Abstract excerpt

PURPOSE: To determine the involvement of p53 in ionizing radiation-induced excision and recombination repair. MATERIALS AND METHODS: Shuttle vector pZ189 containing radiation-induced single strand breaks plus base damage (ocDNA), ultraviolet-radiation damage (uvDNA), or a restriction enzyme-produced double strand break (linDNA) were processed in unirradiated or irradiated p53wt and p53mut lymphoblasts. Mutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to DNA Repair
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Plasmids

Share to Recombination, Genetic

Share to Time Factors

Share to Transfection

Source

Identifiers

PMID: 9712552
DOI: 10.1080/095530098141618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of the involvement of p53 in gamma-radiation-induced DNA repair in human lymphoblasts.PMID 9712552Read ↗

Mutations induced by ionizing radiation in a plasmid replicated in human cells. I. Similar, nonrandom distribution of mutations in unirradiated and X-irradiated DNA.Semantic proximity Read ↗

Dependence of the mutation spectrum in a shuttle plasmid replicated in human lymphoblasts on dose of gamma radiation.Semantic proximity Read ↗

Defective modulation of double-strand break repair in ataxia telangiectasia cells by gamma radiation.Semantic proximity Read ↗

Analysis of mutations induced by replication of UV-damaged plasmid DNA in HeLa cell extracts.Semantic proximity Read ↗

Mutations caused by gamma-radiation-induced double-strand breaks in a shuttle plasmid replicated in human lymphoblasts.Semantic proximity Read ↗

Analysis of N-methyl-N-nitrosourea-induced mutations in a shuttle vector plasmid propagated in mouse O6-methylguanine-DNA methyltransferase-deficient cells in comparison with proficient cells.Semantic proximity Read ↗

Mutations induced by ionizing radiation in a plasmid replicated in human cells. II. Sequence analysis of alpha-particle-induced point mutations.Semantic proximity Read ↗

Ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum lymphoblastoid cells and fibroblasts.Semantic proximity Read ↗

Similarity in the molecular profile of mutations induced by UV light in shuttle vector plasmids propagated in mouse and human cells.Semantic proximity Read ↗

Wild-type p53 reduces radiation hypermutability in p53-mutated human lymphoblast cells.Semantic proximity Read ↗

Gene targeted DNA double-strand break induction by (125)I-labeled triplex-forming oligonucleotides is highly mutagenic following repair in human cells.Semantic proximity Read ↗

Decreased DNA Repair Efficiency by Loss or Disruption of p53 Function Preferentially Affects Removal of Cyclobutane Pyrimidine Dimers from Non-transcribed Strand and Slow Repair Sites in Transcribed StrandSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.