Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein.

doi:10.1046/j.1365-2559.1998.00499.x

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Article

Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein.

Histopathology - 1 Nov 1998

Stewart R L, Royds J A, Burton J L, Heatley M K, Wells M

Abstract excerpt

AIMS: To investigate the mutational status of the p53 gene (Tp53) in endometrial carcinomas expressing p53 protein by direct gene sequencing. METHODS AND RESULTS: Eighteen cases of endometrial carcinoma, selected on the basis of p53 protein expression as detected immunohistochemically by the mono...

Topics

Adenocarcinoma
Aged
Aged, 80 and over
Cell Nucleus
Endometrial Neoplasms
Female
Genes, p53
Humans
Immunohistochemistry
Middle Aged
Mutation
Sequence Analysis
Tumor Suppressor Protein p53

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