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Article

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas.

Human pathology - 1 Oct 1996

Soong R, Robbins P D, Dix B R, Grieu F, Lim B, Knowles S, Williams K E, Turbett G R, House A K, Iacopetta B J

Abstract excerpt

Immunohistochemical (IHC) detection of p53 protein was compared with the presence of p53 gene mutation in many colorectal (n = 100), breast (n = 92), endometrial (n = 122), and gastric (n = 116) carcinomas. Two commercially available antibodies, DO7 and CM1, were used for IHC analysis of paraffin-embedded tissue sections. Screening for gene mutations in frozen and paraffin-embedded tumor samples was carried out...

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PMID: 8892589
DOI: 10.1016/s0046-8177(96)90282-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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