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Article

p53 gene mutation in female genital tract carcinosarcomas (malignant mixed müllerian tumors): a clinicopathologic study of 74 cases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 1994

Costa M J, Vogelsan J, Young L J

Abstract excerpt

Mutations of the p53 suppressor gene are involved in carcinogenesis by inactivating p53 protein (p53P), which is involved in normal cell growth control. Mutant p53P, detectable by immunohistochemistry due to longer half-life as compared to wild-type, is a marker for p53 gene mutation. Seventy-four female genital tract carcinosarcomas (FGTCSs) (41 of the heterologous type exhibiting 33 rhabdomyosarcomatous, 13...

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PMID: 7991520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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