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Article

V(D)J recombinase-mediated HPRT mutations in peripheral blood lymphocytes of normal children.

Cancer research - 15 Mar 1996

Finette B A, Poseno T, Albertini R J

Abstract excerpt

Somatic mutations in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene are rare occurrences in T-lymphocytes of normal individuals. Lacking pathogenic significance, these events can serve as reporters for assessing environmental genotoxicity. The present molecular analyses of hprt mu...

Topics

Adolescent
Age Factors
Base Sequence
Child
Child, Preschool
DNA Nucleotidyltransferases
Exons
Gene Deletion
Humans
Hypoxanthine Phosphoribosyltransferase
Infant
Infant, Newborn
Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Sequence Analysis, DNA

Source

Identifiers

PMID: 8640832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8640832-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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V(D)J recombinase-mediated HPRT mutations in peripheral blood lymphocytes of normal children.PMID 8640832Read ↗

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