Article
Transforming growth factor-beta1 gene polymorphisms and coronary artery disease.
Clinical science (London, England : 1979) - 1 Dec 1998
Syrris P, Carter N D, Metcalfe J C, Kemp P R, Grainger D J, Kaski J C, Crossman D C, Francis S E, Gunn J, Jeffery S, Heathcote K
Abstract excerpt
1. Transforming growth factor-beta1 is a cytokine with a very wide spectrum of biological activities. Previous studies have shown that it is involved in a number of physiological and pathological processes including heart disease. In our study we aimed to scan the transforming growth factor-beta1...
Topics
- Case-Control Studies
- Chi-Square Distribution
- Coronary Disease
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Humans
- Linkage Disequilibrium
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Risk Factors
- Transforming Growth Factor beta