Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians.

Aging cell - 1 Dec 2004

Carrieri Giuseppina, Marzi Erika, Olivieri Fabiola, Marchegiani Francesca, Cavallone Luca, Cardelli Maurizio, Giovagnetti Simona, Stecconi Rosalia, Molendini Cinzia, Trapassi Chiara, De Benedictis Giovanna, Kletsas Dimitri, Franceschi Claudio

Abstract excerpt

Sequence variations in a variety of pro- or anti-inflammatory cytokine genes have been found to influence successful aging and longevity. Because of the role played by the transforming growth factor beta1 (TGF-beta1) cytokine in inflammation and regulation of immune responses, the variability of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Longevity

Share to Sex Characteristics

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 15569360
DOI: 10.1111/j.1474-9728.2004.00129.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15569360-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians.PMID 15569360Read ↗

Association of TGFβ1 codon 10 (T>C) and IL-10 (G>C) cytokine gene polymorphisms with longevity in a cohort of Italian population.Semantic proximity Read ↗

Allele frequencies of +874T-->A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians.Semantic proximity Read ↗

The Genetics of Human LongevitySemantic proximity Read ↗

The role of IL-1 gene cluster in longevity: a study in Italian population.Semantic proximity Read ↗

Inflammation and Genetics: An Insight in the Centenarian ModelSemantic proximity Read ↗

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians.Semantic proximity Read ↗

Gender-specific association between -1082 IL-10 promoter polymorphism and longevity.Semantic proximity Read ↗

+10 T/C polymorphisms in the gene of transforming growth factor-beta1 are associated with neurodegeneration and its clinical evolution.Semantic proximity Read ↗

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians.Semantic proximity Read ↗

Immunogenetics, Gender, and LongevitySemantic proximity Read ↗

Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis.Semantic proximity Read ↗

TNFA gene variants related to the inflammatory status and its association with cellular aging: From the CORDIOPREV study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.