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Article

Polymorphisms in the TNF-alpha and TNF-receptor genes in patients with coronary artery disease.

European journal of clinical investigation - 1 Oct 2001

Allen R A, Lee E M, Roberts D H, Park B K, Pirmohamed M

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) is both multifactorial and polygenic in nature. Atheroma formation, the pathological hallmark of CAD, is an inflammatory process, with pro-inflammatory cytokines, such as tumour necrosis factor-alpha (TNF-alpha), having a major role in its pathogenesis. We have therefore investigated whether polymorphisms in the TNF-alpha (- 238 and - 308), TNF receptor 1 (position - 609...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11737221
DOI: 10.1046/j.1365-2362.2001.00907.x

Genes

TNF
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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