Article
-308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease.
Clinical chemistry and laboratory medicine - 1 Jan 2009
Ghazouani Lakhdar, Khalifa Sonia-Ben-Hadj, Abboud Nesrine, Addad Faouzi, Khalfallah Ali Ben, Brahim Nsiri, Mediouni Mounira, Almawi Wassim Y, Mahjoub Touhami
Abstract excerpt
BACKGROUND: Recent research has shown that inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis. Several lines of evidence support a key role for tumor necrosis factor-alpha (TNF-alpha), a potent immunomodulator and pro-inflammatory cytokine, in the development of atherosclerosis and in complications of CAD. METHODS: We investigated the possible association...
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