Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.

Cell - 22 Aug 1997

Kaghad M, Bonnet H, Yang A, Creancier L, Biscan J C, Valent A, Minty A, Chalon P, Lelias J M, Dumont X, Ferrara P, McKeon F, Caput D

Abstract excerpt

We describe a gene encoding p73, a protein that shares considerable homology with the tumor suppressor p53. p73 maps to 1p36, a region frequently deleted in neuroblastoma and other tumors and thought to contain multiple tumor suppressor genes. Our analysis of neuroblastoma cell lines with 1p and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to DNA-Binding Proteins

Share to Gene Expression

Share to Heterozygote

Share to Molecular Sequence Data

Source

Identifiers

PMID: 9288759
DOI: 10.1016/s0092-8674(00)80540-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9288759-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.PMID 9288759Read ↗

Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.Semantic proximity Read ↗

p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequentSemantic proximity Read ↗

Variable expression and absence of mutations in p73 in primary neuroblastoma tumors argues against a role in neuroblastoma development.Semantic proximity Read ↗

Genomic and allelic expression status of the p73 gene in human neuroblastoma.Semantic proximity Read ↗

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers.Semantic proximity Read ↗

Stage-independent expression and genetic analysis of tp73 in neuroblastoma.Semantic proximity Read ↗

p73, a gene related to p53, is not mutated in esophageal carcinomas.Semantic proximity Read ↗

Frequent inactivation of the <i>p73</i> gene by abnormal methylation or LOH in non‐Hodgkin's lymphomasSemantic proximity Read ↗

p73 mutations are not detected in sporadic and hereditary breast cancer.Semantic proximity Read ↗

P73 expression in neuroblastoma: a role in the biology of advanced tumors?Semantic proximity Read ↗

Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.Semantic proximity Read ↗

p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.