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Article

Different binding of NF-Y transcriptional factor to DQA1 promoter variants.

Human immunology - 1 Dec 1998

Indovina P, Megiorni F, Ferrante P, Apollonio I, Petronzelli F, Mazzilli M C

Abstract excerpt

Polymorphism in the HLA-DQA1 promoter (QAP) sequences could influence the gene expression through a differential binding of transcriptional factors. Considering the main role played by the Y-box in the transcription, we focused on the QAP4 variants differing for a G vs A transition from the QAP Y-box consensus sequence. Electrophoretic Mobility Shift Assay using the two Y-box sequences was performed to determine...

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Source

Identifiers

PMID: 9831131
DOI: 10.1016/s0198-8859(98)00082-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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