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Article

Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype.

Pharmacogenetics - 1 Oct 1998

Powell H, Kitteringham N R, Pirmohamed M, Smith D A, Park B K

Abstract excerpt

Cytochrome P4502E1 (CYP2E1) is constitutively expressed in human liver and is responsible for the metabolic bioactivation of a wide variety of xenobiotics, including a number of protoxins and procarcinogens. CYP2E1 expression is regulated at several levels including pre-transcriptional, transcriptional and post-transcriptional levels, and any variation in enzyme concentration and hence activity may represent...

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PMID: 9825833
DOI: 10.1097/00008571-199810000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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