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Article

Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity.

Journal of toxicology and environmental health. Part B, Critical reviews - 1 Jan 2009

Neafsey Pat, Ginsberg Gary, Hattis Dale, Johns Douglas O, Guyton Kathryn Z, Sonawane Babasaheb

Abstract excerpt

Cytochrome P-450 2E1 (CYP2E1) is a key enzyme in the metabolic activation of a variety of toxicants including nitrosamines, benzene, vinyl chloride, and halogenated solvents such as trichloroethylene. CYP2E1 is also one of the enzymes that metabolizes ethanol to acetaldehyde, and is induced by recent ethanol ingestion. There is evidence that interindividual variability in the expression and functional activity of...

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Identifiers

PMID: 20183527
DOI: 10.1080/10937400903158359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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