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Article

Relative expression of cytochrome <i>P</i>450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

15 Jan 1992

Abstract excerpt

Cytochrome P450s play a central role in the metabolism and disposition of an extremely wide range of drugs and chemical carcinogens. Individual differences in the expression of these enzymes may be an important determinant in susceptibility to adverse drug reactions, chemical toxins and mutagens. In this paper, we have measured the relative levels of expression of cytochrome P450 isoenzymes from eight gene...

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Identifiers

PMID: 1736885
DOI: 10.1042/bj2810359

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