Article
Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.
Pharmacogenetics - 1 Jun 1996
Carrière V, Berthou F, Baird S, Belloc C, Beaune P, de Waziers I
Abstract excerpt
CYP2E1 is involved in the activation of various carcinogens, including N-nitrosamines, which are believed to be important in human carcinogenesis. Humans exhibit wide interindividual variability in levels of CYP2E1 mRNA and protein, which might explain interindividual differences in susceptibilit...
Topics
- Alleles
- Chlorzoxazone
- Cytochrome P-450 CYP2E1
- Genotype
- Humans
- Hydroxylation
- Phenotype