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Article

Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians.

Pharmacogenetics - 1 Dec 1995

Pirmohamed M, Kitteringham N R, Quest L J, Allott R L, Green V J, Gilmore I T, Park B K

Abstract excerpt

Genetic factors may be of importance in determining inter-individual susceptibility to alcoholic liver disease (ALD). Among the candidate genes which have been considered to be important are those which code for enzymes involved in alcohol metabolism. Cytochrome P4502E1 (CYP2E1) metabolizes alcohol to acetaldehyde and the hydroxyethyl radical, and is also inducible by alcohol. A Rsa I restriction fragment length...

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Identifiers

PMID: 8747406
DOI: 10.1097/00008571-199512000-00003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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