Article
CYP2E1 expression in human lymphocytes from various ethnic populations.
Alcoholism, clinical and experimental research - 1 Dec 1999
Raucy J L, Schultz E D, Kearins M C, Arora S, Johnston D E, Omdahl J L, Eckmann L, Carpenter S P
Abstract excerpt
BACKGROUND: Monitoring CYP2E1 levels in alcoholic individuals holds inherent appeal because such determinations might indicate individuals at increased risk for alcoholic liver disease. We previously demonstrated that lymphocyte CYP2E1 expression reflects in vivo activity of the hepatic enzyme. METHODS: To further validate this approach, the current investigation compared lymphocyte CYP2E1 content and...
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