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Article

Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5'-flanking region.

Journal of biochemistry - 1 Aug 1994

Watanabe J, Hayashi S, Kawajiri K

Abstract excerpt

The effects of two genetically associated polymorphisms [c1 allele: PstI -, RsaI +; c2 allele: PstI +, RsaI -] in the 5'-flanking region on the regulation and expression of the human CYP2E1 gene were investigated. DNase I footprinting and CAT activity analyses using various deletion mutants constructed with DNA segments from genotype A (c1/c1) or C (c2/c2) and SV40 or an endogenous promoter showed that the RsaI...

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Source

Identifiers

PMID: 7529759
DOI: 10.1093/oxfordjournals.jbchem.a124526

Genes

CAT
GAPDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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