Article
AT1 receptor A/C1166 polymorphism contributes to cardiac hypertrophy in subjects with hypertrophic cardiomyopathy.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 1998
Osterop A P, Kofflard M J, Sandkuijl L A, ten Cate F J, Krams R, Schalekamp M A, Danser A H
Abstract excerpt
The development of left ventricular hypertrophy (LVH) in subjects with hypertrophic cardiomyopathy (HCM) is variable, suggesting a role for modifying factors such as angiotensin II. We investigated whether the angiotensin II type 1 receptor (AT1-R) A/C1166 polymorphism, the angiotensin-converting...
Topics
- Adult
- Aged
- Aged, 80 and over
- Analysis of Variance
- Biomarkers
- Cardiomyopathy, Hypertrophic
- Enzyme Precursors
- Female
- Genotype
- Humans
- Hypertrophy, Left Ventricular
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Receptor, Angiotensin, Type 1
- Receptor, Angiotensin, Type 2
- Receptors, Angiotensin