Article
Renal function dependent association of AGTR1 polymorphism (A1166C) and electrocardiographic left-ventricular hypertrophy.
American journal of hypertension - 1 Oct 2007
Smilde Tom D J, Zuurman Mike W, Hillege Hans L, van Veldhuisen Dirk J, van Gilst Wiek H, van der Steege Gerrit, Voors Adriaan A, Kors Jan A, de Jong Paul E, Navis Gerjan
Abstract excerpt
BACKGROUND: The association of renin-angiotensin system (RAS) polymorphisms and left-ventricular hypertrophy (LVH) may depend on the presence of risk factors for LVH, such as renal dysfunction. We studied whether renal function modulates the association between RAS polymorphisms and LVH in a cross-sectional study of 8592 inhabitants of Groningen. METHODS: Left-ventricular hypertrophy was determined with...
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