Article
Variants of trophic factors and expression of cardiac hypertrophy in patients with hypertrophic cardiomyopathy.
Journal of molecular and cellular cardiology - 1 Dec 2000
Patel R, Lim D S, Reddy D, Nagueh S F, Lutucuta S, Sole M J, Zoghbi W A, Quiñones M A, Roberts R, Marian A J
Abstract excerpt
Patients with hypertrophic cardiomyopathy (HCM) exhibit variable expression of left ventricular hypertrophy (LVH), a major determinant of mortality and morbidity, which is partly due to the diversity of causal mutations, genetic background (modifier genes), and probably environmental factors. We determined association of functional variants of tumor necrosis factor (TNF)- alpha, interleukin-6 (IL6), insulin-like...
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