Article
Role of angiotensin II type I (AT1 A1166C) receptor polymorphism in susceptibility of left ventricular dysfunction.
Indian heart journal - 1 Jan 2000
Mishra Avshesh, Srivastava Anshika, Kumar Surendra, Mittal Tulika, Garg Naveen, Agarwal Surendra Kumar, Pande Shantanu, Mittal Balraj
Abstract excerpt
BACKGROUND: Left ventricular dysfunction (LVD) with subsequent congestive heart failure (CHF) constitutes the final common pathway for a host of cardiac disorders. The impaired LV function develops in response to an ischemic insult followed by a fall in cardiac output that leads to activation of renin-angiotensin-system (RAS). Angiotensin II type I receptor (AT1), which mediate the vasoconstrictive and...
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