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Article

Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.

Circulation - 1 Oct 1995

Lechin M, Quiñones M A, Omran A, Hill R, Yu Q T, Rakowski H, Wigle D, Liew C C, Sole M, Roberts R

Abstract excerpt

BACKGROUND: The variability of the phenotypic expression of left ventricular hypertrophy (LVH) in patients with hypertrophic cardiomyopathy (HCM) indicates a potential role for additional modifying genes. Variants of angiotensin-I converting enzyme (ACE) gene have been implicated in cardiac hypertrophy. To assess whether ACE genotypes influence the phenotypic expression of hypertrophy, we determined the left...

Topics

Adult
Cardiomyopathy, Hypertrophic
Echocardiography
Female
Genotype
Humans
Hypertrophy, Left Ventricular
Male
Peptidyl-Dipeptidase A
Phenotype
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regression Analysis

Source

Identifiers

PMID: 7671365
DOI: 10.1161/01.cir.92.7.1808

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7671365-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.PMID 7671365Read ↗

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