Article
Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.
Circulation - 1 Oct 1995
Lechin M, Quiñones M A, Omran A, Hill R, Yu Q T, Rakowski H, Wigle D, Liew C C, Sole M, Roberts R
Abstract excerpt
BACKGROUND: The variability of the phenotypic expression of left ventricular hypertrophy (LVH) in patients with hypertrophic cardiomyopathy (HCM) indicates a potential role for additional modifying genes. Variants of angiotensin-I converting enzyme (ACE) gene have been implicated in cardiac hypertrophy. To assess whether ACE genotypes influence the phenotypic expression of hypertrophy, we determined the left...
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