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Article

Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier.

Journal of translational medicine - 1 Jul 2010

Coto Eliecer, Palacín María, Martín María, Castro Mónica G, Reguero Julián R, García Cristina, Berrazueta José R, Morís César, Morales Blanca, Ortega Francisco, Corao Ana I, Díaz Marta, Tavira Beatriz, Alvarez Victoria

Abstract excerpt

BACKGROUND: Angiotensin and serotonin have been identified as inducers of cardiac hypertrophy. DNA polymorphisms at the genes encoding components of the angiotensin and serotonin systems have been associated with the risk of developing cardiovascular diseases, including left ventricular hypertrophy (LVH). METHODS: We genotyped five polymorphisms of the AGT, ACE, AT1R, 5-HT2A, and 5-HTT genes in 245 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Angiotensin, Type 1

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Source

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Identifiers

PMID: 20594303
DOI: 10.1186/1479-5876-8-64
PMCID: PMC2907326

Genes

ACE
AGT
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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