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Article

Impact of renin-angiotensin system polymorphisms on development of systolic dysfunction in hypertrophic cardiomyopathy. Evidence from a study of genotyped patients.

Circulation journal : official journal of the Japanese Circulation Society - 1 Nov 2010

Funada Akira, Konno Tetsuo, Fujino Noboru, Muramoto Akihiko, Hayashi Kenshi, Tsubokawa Toshinari, Sakata Kenji, Kawashiri Masa-Aki, Takeda Yoshiyu, Ino Hidekazu, Yamagishi Masakazu

Abstract excerpt

BACKGROUND: Although the renin-angiotensin system (RAS) can affect the development of left ventricular (LV) hypertrophy, few data exist regarding the relationships between RAS polymorphisms and alteration of LV function. The effect of RAS polymorphisms on LV function in genotyped hypertrophic cardiomyopathy (HCM) was examined in the present study. METHODS AND RESULTS: The study group comprised 126 carriers with...

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Share to Echocardiography
Share to Hypertrophy, Left Ventricular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Peptidyl-Dipeptidase A

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Source

Identifiers

PMID: 20975235
DOI: 10.1253/circj.cj-10-0482

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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