Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese.

doi:10.1111/j.1399-0039.1998.tb03002.x

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Article

Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese.

Tissue antigens - 1 Jun 1998

Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, Itoh K

Abstract excerpt

Polymorphism of the 5'-flanking promoter/enhancer region of the TNF-alpha gene in Japanese is not well understood. To better understand it, we have determined the 1,358 base pair sequence of the 5'-flanking region of the TNF-alpha gene in nine Japanese, and identified three new polymorphisms at p...

Topics

Alleles
Cells, Cultured
Concanavalin A
Gene Frequency
Humans
Japan
Leukocytes, Mononuclear
Mitogens
Polymorphism, Genetic
Promoter Regions, Genetic
Transcription, Genetic
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha

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