Article
Universal Primers for Amplification of TNF-α -308 Promoter Region.
Pakistan journal of biological sciences : PJBS - 1 Jan 2019
Pollo Gracia Alice Victoria, Sumarauw Sarah Celia Pertiwi, Hessel Sofia Safitri, Tallei Trina Ekawati
Abstract excerpt
BACKGROUND AND OBJECTIVE: Genetic variation in the form of a single nucleotide polymorphisms (SNPs) in the tumor necrosis factor alpha (TNF-α) promoter region is known to influence the regulation of TNF-α production, transcription and translation and has been linked to several diseases. Primer sequences that amplify DNA flanking the -308 sequence are not universal, therefore, research on SNP conducted in this...
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