Genetic analysis of second primary lung cancers in patients surviving small cell lung cancer.

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Article

Genetic analysis of second primary lung cancers in patients surviving small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 1996

Kelley M J, Nakagawa K, Conrad N K, LeRiche J, Murray N, Lee J S, Ro J Y, Shaw E G, Tucker M A, Johnson B E

Abstract excerpt

We performed genetic analysis on 12 second primary non-small cell lung cancers in patients surviving small cell lung cancer to assess the potential contribution of smoking to the development of these tumors. Mutations of TP53 were found in three (25%) tumors, KRAS2 in three (25%) tumors, and CDKN...

Topics

Carcinoma, Small Cell
Female
Genes, p53
Genes, ras
Humans
Lung Neoplasms
Male
Middle Aged
Mutation

Source

Open in PubMed

Identifiers

PMID: 9816274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9816274-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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