Article
Combined human papillomavirus typing and TP53 mutation analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.
Head & neck - 1 Jun 2018
Daher Tamas, Tur Mehmet Kemal, Brobeil Alexander, Etschmann Benjamin, Witte Biruta, Engenhart-Cabillic Rita, Krombach Gabriele, Blau Wolfgang, Grimminger Friedrich, Seeger Werner, Klussmann Jens Peter, Bräuninger Andreas, Gattenlöhner Stefan
Abstract excerpt
BACKGROUND: In head and neck squamous cell carcinoma (HNSCC), the occurrence of concurrent lung malignancies poses a significant diagnostic challenge because metastatic HNSCC is difficult to discern from second primary lung squamous cell carcinoma (SCC). However, this differentiation is crucial because the recommended treatments for metastatic HNSCC and second primary lung SCC differ profoundly. METHODS: We...
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