Article
Comparison of p53 and epidermal growth factor receptor gene status between primary tumors and lymph node metastases in non-small cell lung cancers.
Annals of surgical oncology - 1 Feb 2011
Chang Yih-Leong, Wu Chen-Tu, Shih Jin-Yuan, Lee Yung-Chie
Abstract excerpt
BACKGROUND: To obtain insight into the cancer progression and metastatic process, we evaluate p53/epidermal growth factor receptor (EGFR) somatic aberrations in non-small-cell lung cancers to compare accumulated genetic alterations between primary tumors and lymph node metastases. MATERIALS AND METHODS: A total of 56 primary lung cancers with corresponding lymph node metastases were identified to investigate...
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