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Article

Synchronous double primary lung cancers via p53 pathway induced by heavy smoking.

Annals of Saudi medicine - 1 Jan 2000

Lin Cheng-Chih, Chian Chih-Feng, Perng Wann-Cherng, Cheng Ming-Fang

Abstract excerpt

Differences in the histological manifestation of synchronous lung cancers are rare. Synchronous multiple primary lung cancers (SMPLC) are associated with long-term tobacco use, which could independently lead to mutations in the p53 and K-ras genes. We present the case of an 82-year-old man who smoked 30 cigarettes daily for the past 60 years. CT of the chest showed a right upper lobe mass. Bronchoscopy revealed...

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Share to Bronchoscopy
Share to Carcinoma, Non-Small-Cell Lung
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Lung Neoplasms

Share to Neoplasms, Multiple Primary

Share to Small Cell Lung Carcinoma

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Source

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Identifiers

PMID: 20427942
DOI: 10.4103/0256-4947.62837
PMCID: PMC2886876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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