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Article

Anti-p53 antibodies in sera from patients with chronic obstructive pulmonary disease can predate a diagnosis of cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 1996

Trivers G E, De Benedetti V M, Cawley H L, Caron G, Harrington A M, Bennett W P, Jett J R, Colby T V, Tazelaar H, Pairolero P, Miller R D, Harris C C

Abstract excerpt

Serum anti-p53 antibodies (p53-Abs) may be surrogate markers for both p53 alterations and preclinical cancer. Ancillary to a prospective trial to abate progressive development of clinical stages of chronic obstructive pulmonary disease, we conducted a retrospective, nested case-control study. Twenty-three cases were diagnosed with cancer during the trial. Enzyme immunoassay, immunoblotting, and...

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PMID: 9816128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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