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Article

Immunohistochemical detection of mutant p53 protein in small-cell lung cancer: relationship to treatment outcome.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2000

Gemba K, Ueoka H, Kiura K, Tabata M, Harada M

Abstract excerpt

We investigated the expression of mutant p53 proteins in small-cell lung cancer (SCLC) immunohistochemically, by identification of stabilized mutant p53 proteins with a much longer half-life than the wild-type protein. Of 103 tumor specimens obtained by transbronchial tumor biopsy for histologic diagnosis, 52 (50%) showed positive staining for p53 protein with a p53 monoclonal antibody, DO-1. Positive staining...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10880844
DOI: 10.1016/s0169-5002(00)00098-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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