Article
Gene p53 mutations, protein p53, and anti-p53 antibodies as biomarkers of cancer process.
International journal of occupational medicine and environmental health - 1 Jan 2002
Lutz Waldemar, Nowakowska-Swirta Ewa
Abstract excerpt
The finding that gene mutations and changes in their expression form the basis of cancer processes, has prompted molecular epidemiologists to use biomarkers for detecting damaged genes or proteins synthesized under their control in easily available cellular material or systemic liquids. Mutations in the suppressor gen p53 are thought to be essential for cancer development. This gen is one of the most important...
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