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Article

Serum p53 antibodies as early markers of lung cancer.

Nature medicine - 1 Jul 1995

Lubin R, Zalcman G, Bouchet L, Trédanel J, Legros Y, Cazals D, Hirsch A, Soussi T

Abstract excerpt

The p53 alteration is the most common alteration found in human cancer. It usually involves missense mutations that stabilize the p53 protein, which in turn accumulates, reaching levels detectable by immunohistochemistry. We and others have demonstrated that this overexpression of mutant p53 protein can induce a specific humoral response in cancer patients. This result was assessed by the presence of p53...

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Identifiers

PMID: 7585154
DOI: 10.1038/nm0795-701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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