Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 gene mutations are associated with shortened survival in patients with advanced non-small cell lung cancer: an analysis of medically managed patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2000

Murakami I, Hiyama K, Ishioka S, Yamakido M, Kasagi F, Yokosaki Y

Abstract excerpt

Mutations in the p53 gene are common in many cancers. Nevertheless, the relationship between mutations of this tumor suppressor gene and patient survival in non-small cell lung cancer (NSCLC) remains unclear. Interpretation of prior studies of patient outcomes are complicated by the inclusion of both surgical and nonsurgical patients. To better isolate the potential effects of p53 gene mutations per se on tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Multivariate Analysis

Share to Neoplasm Staging

Share to Predictive Value of Tests

Share to Smoking

Share to Survival Analysis

Source

Identifiers

PMID: 10690534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 gene mutations are associated with shortened survival in patients with advanced non-small cell lung cancer: an analysis of medically managed patients.PMID 10690534Read ↗

Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.Semantic proximity Read ↗

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study.Semantic proximity Read ↗

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.Semantic proximity Read ↗

Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non small-cell lung cancer.Semantic proximity Read ↗

p53 exon 5 mutations as a prognostic indicator of shortened survival in non-small-cell lung cancer.Semantic proximity Read ↗

Correlation between the status of the p53 gene and survival in patients with stage I non-small cell lung carcinoma.Semantic proximity Read ↗

Detection of p53 gene mutations in cytopathology and biopsy specimens from patients with lung cancer.Semantic proximity Read ↗

Nondisruptive p53 mutations are associated with shorter survival in patients with advanced non-small cell lung cancer.Semantic proximity Read ↗

Prognostic significance of p53 mutations in non-small cell lung cancer: a meta-analysis of 829 cases from eight published studies.Semantic proximity Read ↗

Detection of p53 mutations in sputum smears precedes diagnosis of non-small cell lung carcinoma.Semantic proximity Read ↗

Immunohistochemical detection of mutant p53 protein in small-cell lung cancer: relationship to treatment outcome.Semantic proximity Read ↗

Mutations in exon 7 and 8 of p53 as poor prognostic factors in patients with non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.