Article
Inhibitors of carbohydrate processing: A new class of anticancer agents.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 1995
Goss P E, Baker M A, Carver J P, Dennis J W
Abstract excerpt
There is a need for anticancer agents with novel mechanisms of action. Recently identified molecular targets for new anticancer agents include inducers of cell differentiation, cell cycle arrest, and apoptosis, as well as signaling pathways for growth factors and cytokines. Another unexplored opp...
Topics
- Animals
- Antineoplastic Agents, Phytogenic
- Carbohydrate Metabolism
- Cell Transformation, Neoplastic
- Clinical Trials, Phase I as Topic
- Drug Design
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors
- Glycoproteins
- Glycosylation
- Humans
- Immunity, Cellular
- Mannosidases
- Mice
- Mutation
- Neoplasm Invasiveness
- Neoplasm Proteins
- Swainsonine