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Article

N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma.

Scientific reports - 21 Nov 2016

Li Jiang-Hua, Huang Wan, Lin Peng, Wu Bo, Fu Zhi-Guang, Shen Hao-Miao, Jing Lin, Liu Zhen-Yu, Zhou Yang, Meng Yao, Xu Bao-Qing, Chen Zhi-Nan, Jiang Jian-Li

Abstract excerpt

Cluster of differentiation 147 (CD147), also known as extracellular matrix metalloproteinase inducer, is a transmembrane glycoprotein that mediates oncogenic processes partly through N-glycosylation modifications. N-glycosylation has been demonstrated to be instrumental for the regulation of CD147 function during malignant transformation. However, the role that site-specific glycosylation of CD147 plays in its...

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PMID: 27869218
DOI: 10.1038/srep35210
PMCID: PMC5116672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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