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Article

Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines

21 Sept 2007

Abstract excerpt

BACKGROUND: Drug resistance is a major problem in cancer chemotherapy. Acquisition of chemo-resistance not only reduces the effectiveness of drugs, but also promotes side effects and markedly reduces the patient's quality of life. However, a number of resistance mechanisms have been reported and are thought to be the reason for the difficulties in solving drug-resistance problems. RESULT: To investigate the...

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PMID: 17883871
DOI: 10.1186/1476-4598-6-58

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