Article
Cytotoxicity and enzymatic activity inhibition in cell lines treated with novel iminosugar derivatives.
Glycoconjugate journal - 1 Feb 2010
Padró Mercè, Castillo José A, Gómez Livia, Joglar Jesús, Clapés Pere, de Bolós Carme
Abstract excerpt
Iminosugars are monosaccharide analogues that have been demonstrated to be specific inhibitors for glycosidases and are currently used therapeutically in several human disorders. N-alkylated derivatives of D-fagomine and (2R,3S,4R,5S)-2-(hydroxymethyl)-5-methylpyrrolidine-3,4-diol with aliphatic...
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