Article
N-linked oligosaccharide processing and autocrine stimulation of tumor cell proliferation.
Experimental cell research - 1 Feb 1991
VanderElst I, Dennis J W
Abstract excerpt
Somatic mutations which impair complex-type N-linked oligosaccharide processing and chemical inhibitors of processing have been shown to reduce metastatic potential in several experimental tumor models. In this report, we demonstrate that glycosylation mutants of the metastatic MDAY-D2 tumor cell line with either truncated glycans lacking sialic acid and galactose or a mutant with less branched N-linked...
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