N-linked oligosaccharide processing and autocrine stimulation of tumor cell proliferation.

doi:10.1016/0014-4827(91)90083-7

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Article

N-linked oligosaccharide processing and autocrine stimulation of tumor cell proliferation.

Experimental cell research - 1 Feb 1991

VanderElst I, Dennis J W

Abstract excerpt

Somatic mutations which impair complex-type N-linked oligosaccharide processing and chemical inhibitors of processing have been shown to reduce metastatic potential in several experimental tumor models. In this report, we demonstrate that glycosylation mutants of the metastatic MDAY-D2 tumor cell...

Topics

Alkaloids
Animals
Carbohydrate Conformation
Carbohydrate Sequence
Cell Division
Clone Cells
Glycosylation
Male
Mice
Mice, Inbred DBA
Molecular Sequence Data
Mutation
Oligosaccharides
Swainsonine
Tumor Cells, Cultured

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