Article
The monomeric guanosine triphosphatase rab4 controls an essential step on the pathway of receptor-mediated antigen processing in B cells.
The Journal of experimental medicine - 16 Nov 1998
Lazzarino D A, Blier P, Mellman I
Abstract excerpt
Each member of the rab guanosine triphosphatase protein family assists in the regulation of a specific step within the biosynthetic or endocytic pathways. We have found that the early endosome-associated rab4 protein controls a step critical for receptor-mediated antigen processing in a murine A2...
Topics
- Animals
- Antigen Presentation
- B-Lymphocytes
- Cell Line
- DNA-Binding Proteins
- Endocytosis
- Endosomes
- GTP-Binding Proteins
- Gene Expression Regulation
- Immunoglobulin G
- Mice
- Microscopy, Fluorescence
- Mutation
- Ovalbumin
- Receptors, Fc
- Repressor Proteins
- Transfection
- Viral Proteins