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Article

A role for the small GTPase Rab21 in the early endocytic pathway.

Journal of cell science - 15 Dec 2004

Simpson Jeremy C, Griffiths Gareth, Wessling-Resnick Marianne, Fransen Jack A M, Bennett Holly, Jones Arwyn T

Abstract excerpt

Rab proteins comprise a family of monomeric GTPases that control cellular membrane traffic. Rab21 is a poorly characterised member with no known function. Human Rab21 cDNA from K562 cells was subcloned into GFP expression vectors to generate Rab21 and Rab21 mutants defective in either GTP hydrolysis (Rab21 Q78L) or binding (Rab21 T33N) for transfection studies in HeLa cells. Confocal fluorescence microscopy and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15561770
DOI: 10.1242/jcs.01560

Genes

EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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