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Article

BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.

European journal of immunology - 1 Jun 2002

Pracht Catrin, Gimborn Kerstin, Reth Michael, Huber Michael

Abstract excerpt

Signal transduction by the B cell antigen receptor (BCR) regulates development, survival and clonal expansion of B cells. The BCR complex comprises the membrane-bound immunoglobulin molecule (mIg) and the Ig-alpha/Ig-beta heterodimer, and was shown to form oligomeric structures. In pervanadate (PV)-treated B cells, multiple proteins are tyrosine phosphorylated upon expression of the BCR, indicating that the BCR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12115644
DOI: 10.1002/1521-4141(200206)32:6<1614::AID-IMMU1614>3.0.CO;2-A

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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