Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.

doi:10.1002/(sici)1520-6866(1998)18:4<183::aid-tcm4>3.0.co;2-d

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Article

Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.

Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1998

Davies M J, Rumsby P C

Abstract excerpt

Human colon cancer is a multistage disease which has been shown to have a number of well-defined histological and genetic events. This knowledge has identified a series of stages in the development of colon cancer in which dietary components and chemicals may play either a beneficial or detriment...

Topics

Animals
Azoxymethane
Carcinogens
Colonic Neoplasms
Male
Mutation
Polymorphism, Single-Stranded Conformational
Precancerous Conditions
Rats
Rats, Sprague-Dawley

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