Article
Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1998
Davies M J, Rumsby P C
Abstract excerpt
Human colon cancer is a multistage disease which has been shown to have a number of well-defined histological and genetic events. This knowledge has identified a series of stages in the development of colon cancer in which dietary components and chemicals may play either a beneficial or detrimental role. Azoxymethane-induced colon cancer in the rat represents a way of investigating such effects on the temporal...
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