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Article

Immunohistochemical demonstration of mutant p53 tumour suppressor gene product in aberrant crypt foci.

Cytobios - 1 Jan 1993

Stopera S A, Bird R P

Abstract excerpt

Mutation of the p53 gene is the most common genetic change accompanying the sequential development of colon cancer, but it has not been studied in the early stages of colon cancer particularly at the single and multiple crypt levels. The expression of the mutant p53 gene product in aberrant crypt foci and in adenocarcinomas induced by azoxymethane was investigated immunohistochemically, using the rat model...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 8319499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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