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Article

Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci.

Cancer letters - 20 Dec 2000

Magnuson B A, South E H, Exon J H, Dashwood R H, Xu M, Hendrix K, Hubele S

Abstract excerpt

The purpose of this study was to compare azoxymethane-induced aberrant crypt foci development in the colons of young and adult rats. Young (4 weeks of age) and adult (50 weeks of age) Sprague-Dawley rats were treated with two weekly injections of azoxymethane or saline. Rats were killed either 6 or 14 weeks following the first injection, and the number, size and location of aberrant crypt foci were determined. At...

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Identifiers

PMID: 11090968
DOI: 10.1016/s0304-3835(00)00609-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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