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Article

Hydrophobic residues in the C-terminal region of S100A1 are essential for target protein binding but not for dimerization.

Cell calcium - 1 Aug 1998

Osterloh D, Ivanenkov V V, Gerke V

Abstract excerpt

S100 proteins are a family of small dimeric proteins characterized by two EF hand type Ca2+ binding motifs which are flanked by unique N- and C-terminal regions. Although shown unequivocally in only a few cases S100 proteins are thought to function by binding to, and thereby regulating, cellular target proteins in a Ca2+ dependent manner. To describe for one member of the family, S100A1, structural requirements...

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Identifiers

PMID: 9803314
DOI: 10.1016/s0143-4160(98)90081-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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