Article
Oligomerization and divalent ion binding properties of the S100P protein: a Ca2+/Mg2+-switch model.
Journal of molecular biology - 30 Oct 1998
Gribenko A V, Makhatadze G I
Abstract excerpt
S100P is a 95 amino acid residue protein which belongs to the S100 family of proteins containing two putative EF-hand Ca2+-binding motifs. In order to characterize conformational properties of S100P in the presence and absence of divalent cations (Ca2+, Mg2+ and Zn2+) in solution, we have analyzed hydrodynamic and spectroscopic characteristics of wild-type and several variants (Y18F, Y88F and C85S) of S100P using...
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