Article
Identification of intracellular target proteins of the calcium-signaling protein S100A12.
European journal of biochemistry - 1 Sept 2004
Hatakeyama Takashi, Okada Miki, Shimamoto Seiko, Kubota Yasuo, Kobayashi Ryoji
Abstract excerpt
In this report, we have focused our attention on identifying intracellular mammalian proteins that bind S100A12 in a Ca2+-dependent manner. Using S100A12 affinity chromatography, we have identified cytosolic NADP+-dependent isocitrate dehydrogenase (IDH), fructose-1,6-bisphosphate aldolase A (aldolase), glyceraldehyde-3-phosphate dehydrogenese (GAPDH), annexin V, S100A9, and S100A12 itself as S100A12-binding...
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